Pavol Jarčuška, Ingrid Urbančíková, Pavol Kristian, Monika Jarčušková
Normal flora contains anaerobic bacteries and facultative anaerobic microorgnisms. Antibiotics affect everywhere in site of penetration to all susceptible microorgnisms. Antibiotic use is the most common factor which leads to destruction and reduction of normal flora. Antibiotics use is associated with reduction of normal flora which leads to recolonization with new microorgnisms. They are in some cases pathogenic and resistant to antibiotics. The most common sequeleae of antibiotic use are diarrhoea and bacterial superinfections of upper respiratory tract. Diarrhoea is frequently recorded in patients which use antibiotics with antianaerobic effect- such as aminopenicillines with inhibitors of betalactamases, lincosamides and many others. Use of probiotics which contain Sacharomyces boulardii, Lactobacillus acidophilus, Bifidobacterium breve, Streptococcus salivarius a Enterococcus fecalis leads to decreasing of diarrhoea incidence in about 52 % and decreasing of travel diarrhoea incidence in 34 %. Effect of probiotics is more expressed in children than in adults.