Miroslav Šašinka, Katarína Furková
Benign familial hematuria is the most frequent form of permanent hematuria. Differential diagnosis is difficult in cases with clear familial occurrence. Despite a good prognosis the children with thin basal membrane syndrome require a long-time monitoring to eliminate the possibility of the early stage of Alport syndrome. The character of genetic changes in other inherited defects of GBM has been disclosed recently and contributed to elucidation of genetic defects of GBM and significantly helped to understand the importance of genetic factors in acquired renal diseases.