Viera Ďurdíková, Peter Ďurdík, Peter Bánovčin
Associated diseases and complications are various in patients with Down syndrome. Redundant gene dose (about 270 genes located on chromosome 21) influences number of various metabolic, hematological and immune reactions. Some diseases are developed intrauterine, other after birth or in adult period. Preventive arrangements and adequate medical care can prevent to develop most of them.