Peter Krcho, Kamila Ilgová, Vanda Chovanová, Iveta Fandáková
Objective: Monitoring of the incidence of early or late neonatal infections is one of the most important method to evaluate
the effectivity of the preventive intervention in neonatal intensive care units.
Methods: Analysis of the incidence of infection complications in newborns treated in neonatal intensive care unit in
2008, 2009 with the comparision in 2016. Every infection complication was selected as early or late, with positive or
negative blood culture, and in the same time compared with the number of newborns treated on invasive ventilation
Results: It was 1105 newborns in the study, all together 1018 blood cultures were analysed in all newborns with increased
risk for infection complications. The incidence of early neonatal infections was in 2,1 percent of cases, the incidence
of late infections was in 9,6 cases. The number of verified late neonatal infection decreased from 10,7 in 2008 to
7,9 percent in 2009 and increased in 2016 to 10,2 percent of cases. In the study the authors compared in the same time
the numbers of newborns on invasive ventilation support (2008 – 56,4 %, 2009 – 67,8 %, 2016 – 46,4 %) as one of the
factor influencing the incidence of late onset neonatal infections.
Conclusion: After the implementation of preventive interventions for late infections it is good to analyse and verify the
infection complications with serial evaluation of the clinical condition, confirmation of the infection and haemoculture
sampling. The implemented preventive interventions could cause decrease of the incidence of late gram-negative neonatal
infections in 2009 compared with the incidence in 2008. The increase of the mainly gram-pozitive infections in
2016 was possible caused by other factors then decreased number of newborns on invasive ventilatory support.