Ivan Martinka, Peter Špalek, Iveta Mečiarová, Martin Lučenič, Ján Radvánszky, Andrea Hergottová, Eva Akubžanová
Thymomas, the tumors of thymus, are typically associated with paraneoplastic autoimmune diseases. About 30%
of thymomas develop myasthenia gravis (MG), 20% of thymomas can be associated with other neurological (polymyositis,
dermatomyositis, neuromyotonia, limbic encefalitis, stiff person syndrome), endocrinological, haematological,
cardiological, rheumatological and skin autoimmune diseases. Myotonic dystrophy type 1 is an autosomal
dominant hereditary muscle disease. We describe in our case study the occurrence of thymoma, three rare autoimmune
diseases in coexistence with myotonic dystrophy type I. in one patient. This disease combination is extremely
rare, and has not been, until now, described in the literature.