Alžbeta Hlucháňová, Vladimír Sodoma, Mário Lazar
Periodic paralyses (PPs) are rare disorders caused by various reasons, which are manifested by attacks of shortterm muscle paralysis, without sensory symptoms and without loss of consciousness(1). We distinguish primary and secondary periodic paralyses. Primary are caused by channelopathies in sodium, calcium and potassium channel genes and include hypokalemic paralysis, hyperkalemic paralysis, and Andersen-Tawil syndrome(2). Secondary can be caused by chronic renal insuficiency, paramyotonia congenita, thiazide or loop-diuretics, tyreotoxicosis and others. We describe a case report of a patient with secondary periodic paralysis as one and only clinical manifestation of tyreotoxicosis.