Janka Jakubíková, Helena Hupková, Jan Trupl, Gabriela Pavlovčinová
Acute otitis media is a very common infection, especially in children up to 5 years of age. S. pneumoniae is the most common pathogen of acute otitis media. Resistant and invasive types are responsible of severe acute otitis media and their complication, including otogene meningitis. The authors introduce results of prospective multi-centric microbiological analysis of acute otitis media (AOM) in children up to 5 years of age in Slovakia. In the study of 133 children S. pneumoniae was isolated in 45.9 %. From isolated strains of S. pneumoniae there were 50.8 % partially or completely resistant to penicillin and 47.5 % of strains were resistant to macrolides. The most common serotypes of S. pneumoniae were 23 F (29.5 %) and 14 (24.6 %), these types also showed the highest resistance to penicillin. When comparing serotypes of S. pneumoniae isolated from middle ear exudates, it was proven that 88,5 % of types are included in 7-valent pneumococcal conjugate vaccine (Prevenar), and all nonvaccination types were sensitive to penicillin.