Téma: 

Dysfunctional bleeding at fertile age

Zuzana Václavová

Dysfunctional uterine bleeding is defined as a variety of bleeding manifestations of anovulatory cycles (in the absence of organic pathology or medical illness). Dysfunctional uterine bleeding is a diagnosis made by exclusion. It is necessary to exclude abnormal uterine bleeding due to pregnancy-related problems (ectopic pregnancy or spontaneus miscarriage), cancer of the cervix and endometrium, endometrial polyps, leiomyomata uteri and infections. Anovulatory menstrual cycles are usually clinical signs of hypothyroidism, hyperprolactinaemia, pituitary-CNS failure or anovulatory cycles due to excessive production of endogenous androgens. Proper differential diagnosis is essential prior to therapy. Dysfunctional uterine bleeding can be cofidently managed without surgical intervention by therapeutic regimens based on sound physiologic principles. By using the pharmacologic application of sex steroids we can reverse the abnormal tissue factors that lead to excessive, irregular and prolonged vaginal bleeding typical of anovulatory cycles.

Ročník 2004  Témy časopisu Gynecology for practice 2 / 2004

CHAIRMAN OF THE EDITORIAL BOARD
MUDr. Tibor Bielik PhD.

MEMBERS OF THE EDITORIAL BOARD
prof. MUDr. Miroslav Borovský, CSc.
prof. MUDr. Ján Danko, CSc.
prof. MUDr. Ľudovít Danihel, PhD.
doc. MUDr. Ivan Hollý, PhD.
MUDr. Ľudovít Janek st.
doc. MUDr. Miroslav Korbeľ, CSc.
prof. MUDr. Štefan Lukačín, PhD.
prof. MUDr. Miloš Mlynček, CSc.
MUDr. Zuzana Nižňanská, PhD.
doc. MUDr. Martin Redecha, PhD.

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doc. MUDr. Martin Redecha, PhD.

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FROM BORDERLINE OF GYNECOLOGY
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MANUSCRIPT REQUIREMENTS

1. An accurate paper title, names and surnames of all authors including titles, authors` workplace. The first author address including the phone number, fax and e-mail address.
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3. Key words - in the extent of 3-6 (just at overview papers, From borderline of cardiology).
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6. Bibliography
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Examples of citations:
1. Webb MJ. Chirurgia v gynekologickej onkológii – včera, dnes a zajtra. Gynekol prax 2003; 1 (1): 29-34.
2. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
3. Kistner RW. Gynecology. Principles and Practice. 3rd Ed. Chicago: Year Book Medical Publisher 1979: 823p.
4. Osborne BE.The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.
5. Rodička a novorodenec 2000. Zdravotnická statistika, ÚZIS ČR 2001, 127.
6. http/www.nspnz.sk/neonatal/priority.htm

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For primary dysmenorrhoea from laboratory results it is characteristic:
a. increase of lymphocytes in differential BP over 40 %
b. increase of C-reactive protein and FW in the blood
c. decrease of Hb level in the blood below 100 g/l
d. none of them are characteristic

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