Karol Dókuš, Kristína Biskupská-Boďová, Martina Cuľbová, Miroslav Haško
Major congenital anomalies remain a leading worldwide cause of perinatal mortality and infant deaths at a later age. Over the past 2 or 3 decades there have been significant advances in the field of perinatology with prenatal diagnostics becoming its distinguished part. The present screening practice enables us to disclose a considerable amount of major congenital anomalies in utero thus giving us the opportunity to control their natural course and therapy, if available. The authors intended to draw attention to the effectiveness of a routine ultrasound screening in the 2nd trimester of pregnancy. On the ground of clarity the description of the most frequent anomalies follows a topographical aspect.