Medicine of upcoming decades will be confronted with challenges arising from getting the general population older.
Together with progress of aging of whole organism the immunologic health is decreasing, infectious diseases are arising,
thus the vaccination of seniors is more and more actual. One of preventable diseases is herpes zoster (HZ). Its incidence
is increasing with age and can affect up to 20 % of people older than 60 years. Immunocompromised persons
are most risky. A redoubtable complication of HZ is post‑herpetic neuralgia (PHN) occurring in every third‑fourth patient.
HZ vaccine significantly reduces incidence of HZ. In the case not preventing it, complications, including PHN, are