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Časopis Clinical urology – Článok Risk of secondary malignancies after therapy for testicular tumours

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Téma: 

Risk of secondary malignancies after therapy for testicular tumours

Hana Šiffnerová, Dana Králová

Objective: The work is aimed at the occurrence of secondary malignancies after therapy for primary testicular tumours. The target of the work was determination of the number and type of secondary tumours, their effect on the survival and comparison of relative risk of the origination of secondary tumours depending on particular treatment modalities. Material and methods: Total of 313 patients with testicular tumours were assessed, who experienced orchiectomy in 1968 to 1998 with subsequent irradiation, chemotherapy or combination of the two modalities. Statistical methods comprised the survival analysis by Kaplan-Meier, the Fisher test, squared Chi test, log-rank test and determination of relative risks. Results: Total of 22 secondary tumours, i.e. 7 % were found in the group. The relative risk of the secondary malignancy development was of 1.04. The median time till the secondary tumour occurrence was of 143 months (41 - 418 months). Total of 7 tumours, i.e. 2,2 %, were found in the contralateral testicle with the median time till the secondary tumour occurrence of 32 months (1 - 65 months). Total of 213 patients were subjected to radiotherapy, which was associated with enhanced risk of the secondary tumour development (RR = 8.38), especially for tumour of the pancreas, melanoblastoma and tumour of the rectosigmoideum. The risk in 100 patients treated by chemotherapy was low (RR = 0.38). Conclusion: Most patients with testicular tumours have long-term prognosis and thus, it is desirable to know the risk of secondary malignancies and to include it into plan of long-term subsequent follow-up.

Klin. urol. 2008; 4 (1): 15 - 18
CELÝ OBSAH ČLÁNKU JE DOSTUPNÝ IBA PRE PRIHLÁSENÝCH PREDPLATITEĽOV Prihlásiť sa

Témy časopisu Clinical urology 1 / 2008

Case Studies

Nie sú dostupné žiadne voľne dostupné články
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prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
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MUDr. Peter Zvara, PhD.

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2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Which of following factors is not related to rosacea?
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Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year