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Časopis Clinical urology – Článok Combination therapy of alpha-blocker and tolterodin er in patients with benign prostatic obstruction and overactive bladder

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Téma: 

Combination therapy of alpha-blocker and tolterodin er in patients with benign prostatic obstruction and overactive bladder

1Ján Švihra, 2Ivana Zigová, 3Ján Šebo, 4Ondrej Hajdúk, 5Peter Piovarči

Objective: The objective of this study was to assess the efficacy and tolerability of tolterodine ER in combination with any alphablocker in the treatment of the benign prostatic obstruction and overactive bladder (OAB). Materials and methods: This study was a prospective, non-interventional drug monitoring program in the context of which subjects received treatment with tolterodine ER while they continued to take their alpha1-blockers. When a patient was enrolled in the study for his pathological condition, then all the demographic data, indication diagnosis, previous therapy as well as other previous and concomitant medication and general history were recorded. At the final examination the number of frequency, urgency, nocturia, urge incontinence and acute urinary retention episodes with regard to the efficacy of tolterodine ER was recorded. Results: 495 patients with benign prostatic obstruction and overactive bladder were enrolled, 478 (96.6 %) subjects completed the study treatment. The majority of clinicians or patients rated the study medication as excellent (299/492; 60.8 % or 336/492; 68.3 %). The number of frequency episodes per 24 hours decreased from the mean baseline value of 12.72 to 8.16 at final visit. The number of incontinence episodes per 24 hours decreased from the mean baseline value of 2.02 to 0.64 at final visit. The number of nocturia episodes decreased from the mean baseline value of 3.73 to 1.35 at final visit. There were no deaths or serious adverse events in this study. Conclusion: At the final visit a decrease in the mean number of episodes of all OAB symptoms was observed. The majority of clinicians and patients rated the treatment as excellent. Treatment with tolterodine ER was generally well-tolerated.

Klin. urol. 2009; 5 (1): 19-23
CELÝ OBSAH ČLÁNKU JE DOSTUPNÝ IBA PRE PRIHLÁSENÝCH PREDPLATITEĽOV Prihlásiť sa

Ročník 2009  Témy časopisu Clinical urology 1 / 2009

Case Studies

Nie sú dostupné žiadne voľne dostupné články
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prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
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prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

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prof. MUDr. Ján Švihra, PhD.

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The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy. Maximum extent is 7 pages of text (font ARIAL or TIMES, font size 12, line spacing 1.5). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office.

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Do not use "ét al.", but state all authors.

Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Which of following factors is not related to rosacea?
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The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

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Send contributions in the e-mail to the address: paulenova@amedi.sk
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year