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Časopis Clinical urology – Článok Outcomes of retroperitoneal lymph node dissection in patients with metastatic nonseminomatous germ cell cancer of testis

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Téma: 

Outcomes of retroperitoneal lymph node dissection in patients with metastatic nonseminomatous germ cell cancer of testis

Ondřej Havránek1, Jan Krhut1, Jaroslav Hájek2, Jozef Kopecký1, David Feltl2

Objective: To evaluate oncological results and functional results of modified retroperitoneal lymhadenectomy with resection limited to enlarged residual lymph nodes in patients after chemotherapy for metastatic nonseminomatous germinal cell testicular cancer. Material and methods: We made a retrospective study in 14 patients undergoing retroperitoneal lymphadenectomy for residual tumour in the retroperitoneum after chemotherapy for nonseminomatous testicular cancer between 2000-2006. Average age was 33.4 years, average follow up after surgery 56 months. Eight patients (57.1 %) were treated by 3-4 cycles of the first line chemotherapy (CHT) and 6 patients underwent surgery after next 2-5 cycles of the second line CHT. The extend of surgery was limited to macroscopically enlarged lipolymphatic tissue. Results: Histology showed necrosis in 11 cases (78.6 %) and viable carcinoma in 3 cases (21.4 %). Ten patients with negative histology were observed. One patient with positive histology was treated by radiotherapy and 2 patients with positive histology received adjuvant CHT. All patients have preserved ejaculation after surgery. All of the patients are surviving without progression of the disease. Conclusion: Both classical bilateral and modified retroperitoneal lymphadenectomy in patients after CHT for nonseminomatous testicular cancer is a procedure with high risk of peri- and postoperative morbidity. Modified procedure with resection of enlarged residual lymph node only may reduce the risk of postoperative morbidity. Especially it can preserve the physiological ejaculation. The oncological outcomes were similar with procedures with standard extend of lymphadenectomy.

Klin. urol. 2011; 7 (2-3): 64-67
CELÝ OBSAH ČLÁNKU JE DOSTUPNÝ IBA PRE PRIHLÁSENÝCH PREDPLATITEĽOV Prihlásiť sa

Ročník 2011  Témy časopisu Clinical urology 2 / 2011

Nie sú dostupné žiadne voľne dostupné články
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prof. MUDr. Ján Kliment, CSc.

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prof. MUDr. Ján Breza, DrSc.
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prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

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prof. MUDr. Ján Švihra, PhD.

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Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year