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Časopis Clinical urology – Článok Obesity and prostate cancer

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: 

Obesity and prostate cancer

Terézia Jankovichová, Martin Jankovich

Objective: Prostate cancer represents one of the most common malignancies in men and one of the most common
causes of death from an oncologic disease. Obesity epidemic represents actual medical, social and economic problem.
The association of obesity as a risk factor for prostate cancer remains unclear, however correlation between obesity and
development of aggressive forms of prostate cancer and progression of the disease is supposed. The aim of this review
is to assess the correlation between obesity and prostate cancer based on available scientific information.
Material and methods: Searching and analysis of data available in electronic medical databases.
Results: Analysis of studies showed that obesity could be a predictor of aggressive forms of prostate cancer. Studies
analysing relation between obesity and prostate cancer demonstrated elevated risk of development of prostate cancer
especially when correlated with BMI and waist circumference despite of certain inhomogeneity. The positive correlation
of metabolic syndrome and aggressive tumour forms was also demonstrated. The research of possible molecular
mechanisms causing this relation did not show convincing results. Leptin level correlated with aggressive tumour
forms, activity of leptin was independent of presence of leptin receptors in tumour tissue. Insulin and IGF1 pathway
might be a possible connection between metabolic syndrome and prostate cancer but more detailed research is needed.
Conclusions: Obtained data suggest that obesity is an independent risk factor of aggressive and advanced forms of prostate
cancer influencing cancer specific mortality. Molecular mechanisms of this relation are not fully understood and
more research is needed.

prostate cancer, obesity, metabolic syndrome, incidence, mortality
Klin. urol. 2015; 11 (1): 14-16

Ročník 2015  Témy časopisu Clinical urology 1 / 2015

Jana Katolická
Terézia Jankovichová, Martin Jankovich

Jaroslav Ženíšek
Ján Švihra, Martin Benčo, Róbert Dušenka, Ján Ľupták, Ján Kliment
Martin Jankovich, Terézia Jankovichová

Jozef Marenčák, Rudolf Moro, Dymitry Lapatko, Michaela Trabalíková

Juraj Fillo, Michaela Levčíková, Ján Luha, Ján Breza, Anna Vachulová, Štefan Durdík, Peter Labaš, Martina Ondrušová
Jozef Marenčák
Silvester Galo, Pavol Žúbor, Soňa Kulichová, Dana Rybárová
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Nie sú dostupné žiadne voľne dostupné články
CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

MEMBERS OF THE EDITORIAL BOARD
prof. Andrzej Borówka, M.D., PhD.
prof. MUDr. Ján Breza, DrSc.
prof. MUDr. Peter Bujdák, PhD.
prof. MUDr. Tomáš Hanuš, DrSc.
doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
prof. MUDr. Ladislav Valanský, PhD.
doc. MUDr. František Záťura, PhD.
MUDr. Peter Zvara, PhD.

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prof. MUDr. Ján Švihra, PhD.

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Examples of citations:
1. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285: 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

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Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné