Vincent Nagy, Miroslav Iláš, Ladislav Valanský, Ľubomír Lachváč, Jaroslav Beck, Vladimíra Sobolová, Patrícia Horváthová, Lucia Kišáková
Objective: To evaluate the most common surgical complications of radical cystectomy with urinary diversion.
Material and Methods: We retrospectively evaluated 72 patients (16 women, 56 men) from the years 2000-2017. The indication for surgery was invasive and recurrent noninvasive high grade bladder cancer. Age of patients: 39-78 years, average 61 years. Urine was derived as follows: ureteroileostomy (Bricker) in 63 (87.5%), orthotopic urinary derivation (Studer) in 7 (9.7%), ureterosigmoidostomy in 1 (1.4%) and nephrostomy of the transplanted kidney in one (1.4%) patient.
Results: The pTNM classification in 72 patients was as follows: pT0 - no patient, pTIS 2 (2.8%), pT1-8 (11.1%), pT2-23 (31.9%), pT3-26 (36,1%), pT4-13 (18,1%), pN0-58 (80,6%), pN1-5 (6,9%), pN2-8 (11,1%), pN3-1 (1,4%), M0-70 (97,2%), M1a-2 (2,8%). Complications occurred in 42 (58,3%) patients. Early complications within 3 months were as follows: acute pyelonephritis in 10 (13.9%), operative wound dehiscence in 7 (9.7%), urinary fistula in 5 (6.9%), ileous condition 2 (2, 8%), diffuse peritonitis 2 (2.8%), enterocutaneous fistula 1 (1.4%), hematoma 1 (1.4%), lymphocele 1 (1.4%), enterorhagia 1 (1.4%), abscess 1 (1.4%). Late complications over a 3-month period: ileus with subsequent resection of ileum 1 (1.4%), abscessing pyelonephritis with nephrectomy in 2 (2.8%), ureteral strictures with hydronephrosis requiring surgery in 6 (8.3%) patients, local and generalized metastases in 12 (16.7%) patients. In 3 (4.2%) patients, we made a secondary uretrectomy for metachronic carcinoma of the urethra. Perioperative mortality within 30 days: 2 (2.8%) and mortality within 90 days: 1 (1.4%) patient.
Conclusion: Radical cystectomy with urinary derivation is associated with significant morbidity. Complications are acceptable with regard to the long-term outcome