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Časopis Clinical urology – Článok Duloxetine and exercise of pelvic floor muscle in women with stress urinary incontinence – the randomized multicentre study

Clinical urology

Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
1336-7579
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné
Téma: Funkcional urology

Duloxetine and exercise of pelvic floor muscle in women with stress urinary incontinence – the randomized multicentre study

Magdaléna Hagovská, Ján Švihra, Ján Breza jr., Jozef Dubravický, Marek Vargovčák

Objective: Our study aimed to evaluate the effect of a combination of innovative pelvic floor muscle training (iPFMT) and duloxetine compared to duloxetine alone in women with stress urinary incontinence (SUI) after 12 weeks of treatment.
Methods: This study was a randomised intervention, parallel, multicentre study in collaboration with 45 urological outpatient clinics at the national level. Patients were assigned in a 1:1 ratio to the experimental and control groups using simple randomisation. The experimental group received oral treatment with duloxetine at a daily dose of 2 x 40 mg and was required to perform iPFMT. The control group received the same oral duloxetine treatment (2 x 40 mg a day) but not presented iPMFT. Data were collected from both groups before the intervention and after the 12-week intervention. Investigation methods were incontinence episode of frequency during the week (IEF), International Consultation on Incontinence Questionnaire (ICIQ – UI SF), Overactive bladder questionnaire (OAB-q), The Incontinence quality of life questionnaire (I-QoL), Patient Global Impression (PGI-I).
Results: There were 158 enrolled women. The final group consisted of 64 women in the control group (56.8 ± 13.8) and 65 women in the experimental group (53.4 ± 11.9). There were no significant differences between groups before treatment. After 12 weeks of treatment there were substantial differences in the experimental group vs control group (p < 0.001), decrease in IEF (66.7% vs. 50.0%), the reduction in ICIQ-UI SF (8.3 ± 38 vs. 9.7 ± 4.2), improved PGI-I (70.8% vs. 65.6%) and total I-QoL score (19.3% vs. 6.6%).
Conclusion: Addition of PFMT to duloxetine treatment significantly improves SUI compared to duloxetine alone.

duloxetine, pelvic floor exercise, urinary incontinence
Klin urol 2020; 16 (1): 27 – 32

Ročník 2020  Témy časopisu Clinical urology 1 / 2020

Urological oncology

Ján Kliment, Katarína Baluchová, Marián Grendár, Boris Eliáš, Roman Mráz, Peter Čech, Klaudia Holečková, Ján Kliment Jr., Henrieta Drobková
Ján Ľupták, Ján Šulgan, Boris Eliáš, Ján Kliment, sen., Ján Švihra, sen., Ján Kliment jr., Igor Sopilko, Roman Tomaškin, Anna Rašková, Pavol Slávik

Funkcional urology

Magdaléna Hagovská, Ján Švihra, Ján Breza jr., Jozef Dubravický, Marek Vargovčák
Magdaléna Hagovská, Ján Švihra, Ján Breza jr., Jozef Dubravický, Marek Vargovčák
Jozef Marenčák
Michal Kmak

Case studies

Matúš Richnavský, Vincent Nagy, Martin Hrivňák, Ľubomír Lachváč, Andrej Bӧӧr
Vincent Nagy, Hedviga Wagnerová, Dana Nagyová, Helena Baumöhlová
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CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ján Kliment, CSc.

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doc. MUDr. Ladislav Jarolím, CSc.
doc. MUDr. Ján Ľupták, PhD.
doc. MUDr. Jozef Marenčák, PhD.
doc. MUDr. Ivan Minčík, PhD.
prof. MUDr. Dalibor Ondruš, DrSc.
prof. Imre Romics, M.D., PhD.
doc. MUDr. Vladimír Študent, PhD.
prof. MUDr. Ján Švihra, PhD.
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Period 3x per year
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The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Clinical urology
Clinical urology
Postgraduate scientific medical journal. Magazine Slovak Association of Urology.
Period 3x per year
Predplatné