Alexandra Filkászová, Peter Štenc, Christian Bartko, Ján Škultéty, Jozef Oravec, Rastislav Sysák, Gabriela Šustová, Sylvia Redechová, Monika Dugátová, Ľubica Hammerová
Uterine sarcomas are rare and comprise only 3% of all uterine cancers, 8% of malignant uterine tumours. Within the
group of soft tissue sarcomas they occur in 7% of all cases. They consist of different histological subtypes as leiomyosarcoma,
endometrial stromal tumour, undifferentiated sarcoma, pure heterologous sarcoma and mixed epithelial and
mesenchymal tumour. Standard treatment for localised disease is an abdominal hysterectomy. Bilateral salpingo-oophorectomy
and lymphadenectomy have no proven values in leiomyosarcomas and undifferentiated sarcomas. However,
in endometrial stromal tumours salpingo-oophorectomy is recommended according to their hormonal responsiveness.
Therapy of carcinosarcomas is according to current recommendations as in the treatment of epithelial uterine
tumours – a standard is hysterectomy, salpingo-oophorectomy, pelvic and paraaortic lymphadenectomy and omentectomy(
Radiotherapy, chemotherapy and hormonal therapy are also included in the multimodal treatment of uterine sarcomas.