Téma: Original Works

Glatiramer acetate for multiple sclerosis treatment already in slovakia

Ľubica Procházková

Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system with various clinical presentations. The main aim of treatment of the relapsing-remitting form of multiple sclerosis (RR MS) is to decrease the disease activity, i.e. to reduce the number of attacks, to slow the progression of disability adversely affecting patients’ quality of life. Apart from interferon beta, which has been used in treatment since 1993, also glatiramer acetate has been available for patients with the relapsing-remitting (RR) form of multiple sclerosis since l996. Glatiramer acetate, an immuno-modulation product based upon amino acid structure of myelin basic protein (MBP), represents one of the first possibilities of antigen-specific therapy for multiple sclerosis. Since April 1st 2006 it has been available also for patients in the Slovak Republic as a first-choice drug for RR MS.

Ročník 2007  Témy časopisu Neurology 3 / 2007

CHAIRMAN OF THE EDITORIAL BOARD
doc. MUDr. Miroslav Brozman, CSc.

MEMBERS OF THE EDITORIAL BOARD
MUDr. František Cibulčík, CSc.
doc. MUDr. Eleonóra Klímová, CSc.
doc. MUDr. Pavol Kučera, PhD.
MUDr. Marian Kuchar, PhD.
doc. MUDr. Robert Mikulík,Ph.D., FESO
MUDr. Vladimír Nosáľ, PhD.
MUDr. Ľubica Procházková, CSc.
prof. MUDr. Bruno Rudinský, CSc.
doc. MUDr. Daniel Šaňák, Ph.D.
doc. MUDr. David Školoudík, Ph.D., FESO
prof. MUDr. Karel Šonka, DrSc.
doc. MUDr. Peter Špalek, PhD.
Dr. Milan R. Voško, PhD.

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SECTIONS

OVERVIEW PAPERS
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6. Bibliography
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Examples of citations:
1. Pitt B, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 1999; 341: 709-717.
2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
5. Osborne BE. The electrocardiogram of the rat. In: Budden R, Detweiler DK, Zbinden G. The rat electrocardiogram in pharmacology and toxicology. Oxford: Pergamon Press 1981: 15-27.

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Which of following factors is not related to rosacea?
a. genetic predisposition
b. Scandinavian origin
c. propionibacterium acnes
d. endothelial growth factor

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