Roman Margóczy, Martin Hudec, Tomáš Forgon, Milan Trenčan
Non-ST elevation myocardial infarction presents a heterogeneous group of patients with different risk profile. Short-term mortality is lower than in STEMI patients, but yearly mortality is doubled. Risk stratification is important for proper therapeutic approach. GRACE is widely used ischaemic risk scoring system with most important components of high risk – recurrence of chest pain, electrical and haemodynamic instability with high necessity of urgent invasive approach. NSTEMI patients with the lowest risk profile should be initially managed conservatively; patients in moderate risk need early invasive management. On the other side, very important is the assessment of bleeding risk (CRUSADE score), to choose the best treatment strategy with the best possible risk/benefit ratio for the patient and to avoid bleeding complications leading to blood transfusions and surgical treatment of bleeding, worsening the patient´s outcome.