P. Harbulák
An age factor plays an increasingly important role in infertility treatment. The parameters
of the ovarian reserve decrease with advanced maternal age. Ovarian reserve
is a functional potential of the ovary, which reflects a number and quality of oocytes
located in it. There are various markers used for the estimation of the ovarian
reserve and currently the most informative and reliable are the following: a hormone
marker – Anti-Műllerian Hormone (AMH) and a sonographic marker assessing
a number of antral follicles of the ovary – Antral Follicle Count (AFC). Cut-off values
regarding reproductive prognosis allow quite accurately determining decreased ovarian
reserve and unfavourable prognosis in ovarian stimulation. Age and markers of
ovarian reserve are significant factors of pregnancy prediction. They are an important
part of infertility diagnosis and indicate considerably a treatment procedure.