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Časopis Slovak Gynecology and Obstetrics – Článok THE ROLE OF ANGIOGENIC FACTORS IN THE PREDICTION OF PREECLAMPSIA

Slovak Gynecology and Obstetrics

Magazine Slovak Association of Gynecology and Obstetrics
Period 4x per year
1335-0862
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Slovak Gynecology and Obstetrics
Slovak Gynecology and Obstetrics
Magazine Slovak Association of Gynecology and Obstetrics
Period 4x per year
Téma: Overview works

THE ROLE OF ANGIOGENIC FACTORS IN THE PREDICTION OF PREECLAMPSIA

B. BOLERÁZSKA, V. DUDIČOVÁ, A. BIRKOVÁ, B. HUBKOVÁ

Nowadays, the disorder of placentation is accepted as a key factor of preeclampsia, which causes dysbalance of antiangiogenic and proangiogenic factors and those penetrate to the systemic circulation of a mother and so influence the whole her organism. The vascular endothelial growth factor (VEGF) and placental growth factor (PIGF) are proangiogenic factors contributing to the normal proliferation of a trophoblast and its nidation. The placenta is a source of these substances. Placental cells also release soluble isoform Flt-1 (sFlt-1), which fulfils the role of an anti-angiogenic factor in the neutralization of PlGF and VEGF effects. Overproduction of sFlt-1 is responsible for dysfunction in the organism of a mother, which causes peripheral vasoconstriction in the effort to increase the mother’s blood pressure. The knowledge of the pathogenesis of this disease open the way to knowledge of laboratory markers in diagnosis and screening of preeclampsia.

Slov. Gynek. Pôrod., 27, 2020, s. 10 – 13

Ročník 2020  Témy časopisu Slovak Gynecology and Obstetrics 1 / 2020

Overview works

Case studies

Nie sú dostupné žiadne voľne dostupné články
SENIOR EDITOR
doc. MUDr. Martin Redecha, PhD.

EDITORIAL BOARD
prof. MUDr. Miroslav Borovský, CSc.
prof. MUDr. Ján Danko, CSc.
prof. MUDr. Karol Holomáň, CSc.
MUDr. Ľudovít Janek
prof. MUDr. Štefan Lukačín, PhD.
prof. MUDr. Miloš Mlynček, CSc.
prof. MUDr. Ján Štencl, CSc.
doc. MUDr. Ivan Hollý, CSc.
doc. MUDr. Miroslav Korbeľ, CSc.
doc. MUDr. Jozef Višňovský, PhD.
doc. MUDr. Pavol Žúbor, DrSc.
doc. MUDr. Igor Rusňák, PhD.
MUDr. Jozef Adam
MUDr. Tibor Bielik, PhD.

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Slovenská gynekologicko-pôrodnícka spoločnosť
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IČO 31802800, DIČ 2021515243
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telefón: 02/55 64 72 48
mobil: 0911 117 949
e-mail: ekonom@amedi.sk
Period 4x per year
1335-0862
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Slovak Gynecology and Obstetrics
Slovak Gynecology and Obstetrics
Magazine Slovak Association of Gynecology and Obstetrics
Period 4x per year