A. Totka, M. Gábor, Ľ. Argalášová, M. Šimko
The epidemic of obesity is currently the most critical global health problem. Currently,
obesity affects approximately one third of reproductive age women, which leads
to a high incidence of obesity during pregnancy. Pregnancy obesity affects the
regulation of placental hormones and via signalling molecules affects the function of
trophoblast, growth and foetal development. There is an association between obesity
and infertility. The cause is an elevated insulin level that affects ovarian function
and an endometrial mucosal effect and ovulation.
A healthy lifestyle, balanced diet and regular physical activity could help reduce
the overweight of women, resulting in homeostasis of adipokines and other placental
hormones necessary for the fate of further foetal development during pregnancy.