Téma: 

Biliary cysts and cholangiocarcinomas

Anton Vavrečka

Biliary cyst are rare with predominating occurrence in females of the Asian population. More than 60 % bile duct cysts are diagnosed in the first decade of life; about 20 % go undiagnosed into adulthood. The cause of biliary cyst has been disputed. Based on clinical and experimental data, genetic (congenital malformation theory) and acquired factors (long common channel theory) may be involved. Biliary cysts are classified according to the site, extent and shape of cystic anomaly. Most complete and practical classification recognizes five types of bile duct cysts. Clinical presentation is a little different in children and adults. The most frequent symptoms are intermittent icterus, abdominal pain and cholangitis, in children palpable mass in abdomen. Basic for diagnosis are clinical symptoms and imaging methods (MRCP and ERCP). The most serious complication is cholangiocarcinoma, which represents a 20-to 30-fold risk in patients with biliary cyst compared to the general population. Biliary cyst treatment is surgical with complete primary cyst excision with Roux-en-Y hepaticojejunostomy reconstruction and cholecystectomy. For Caroli´s disease sometime liver transplantation may be an _option. The complete cyst resection and cholecystectomy is the best prevention for arise of carcinoma.

Ročník 2009  Témy časopisu Gastroenterology for practice 2 / 2009

CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Rudolf Hyrdel, CSc.

MEMBERS OF THE EDITORIAL BOARD
doc. MUDr. Marian Bátovský, CSc., mim. prof. SZU
prof. MUDr. Juraj Bober, CSc.
MUDr. Ivan Bunganič
prof. MUDr. Petr Dítě, DrSc.
doc. MUDr. Martin Huorka, CSc.
doc. MUDr. Peter Makovník, CSc.
MUDr. Juraj Májek, PhD.
prof. MUDr. Peter Mlkvý, CSc.
MUDr. Tomáš Šálek
MUDr. Renata Szépeová, PhD.
prof. MUDr. Anton Vavrečka, CSc.
MUDr. Mária Zakuciová

EDITOR-IN-CHIEF
Ing. Danica Paulenová
e-mail: paulenova@amedi.sk

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SECTIONS

SURVEY WORKS
The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy.
Maximum size is 8 pages (font size 12, line spacing 1.5) with maximum five pictures (graphs). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office. Write the article with focus on its practical use for gastroenerologists and specialists from other disciplines interested in gastroenterology.

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Write the paper on computer in any common text editor.
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MANUSCRIPT REQUIREMENTS

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Citations are numbered chronologically in bold, references in the text are stated by the number of citations in parentheses. Use maximum 20 citations.

Examples of citations:
1. Vaughan TL, Davis S, Kristal A, et al. Obesity, alcohol and tobacco risk factors for cancers of esophagus and gastric cardia :adenocarcinoma versus squamous cell carcinoma Cancer Epidemiol Biomarkers Prev 1995; 4: 85-92.
2. Gao YT, McLaughlin JT, Gridley T, et al. Risk factors for esophageal cancer in Shanghai, China. Role of diet and nutrients. Int J Cancer 1994; 58: 197-202.
3. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.

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AUTODIDACTIC TEST

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

Origination of pigment stones is related to:
a. acute haemolysis
b. chronic haemolysis
c. hypercalcaemia
d. hyperlipoproteinaemia

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are double reviewed.

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Due to practical focus of the journal we would like to ask you to write the paper comprehensively, with emphasis on practical use of provided information in out-patient practice of gastroenterologists and related specialisations.

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