Martina Ondrušová, Rudolf Hrčka, Dalibor Ondruš
Slovak Republic (SR) reach up one of the highest recorded incidence rates of colorectal cancer in the world. The trend of stabilization or decline of the disease number both in males and females has not been confirmed yet in the SR (despite the opportunistic screening carried out since 2002) and the disease incidence has rising tendency. Probable cause of increasing incidence in the SR might be poor participation on preventive examination reaching 15 % over 5 years. In analysis of standardized mortality time trends in 1980-2005 in the SR the significant increase in males and females was found out. However, in females the decline of mortality rates in the last assessed years was reported, most likely as the impact of early disease diagnosis using screening tests and improvement of the disease treatment (with subsequent better survival). In the SR in both sexes clinical stage II is noted most frequently, also the decrease of the disease number in the clinical stage I and in undefined stage was recorded. The trends in risk factors of colorectal cancer in the SR would support the hypotheses of the later culmination of incidence and on the higher levels than in other developed countries. The purpose of this study is to analyze the character and changes in development of incidence, mortality and clinical stages of colorectal cancer (1980-2005) and to compare the results with selected world countries.