Ľudovít Lukáč, Tibor Hlavatý, Elena Chudová, Jana Sobotová, Iveta Čierna, Peter Labaš, Marián Vician, Martin Huorka
Review article presents current knowledge of heredity, clinical signs and therapy of familal adenomatous polyposis (FAP). Describes history of the discovery of this disease, clinical signs, symptoms and colonic and extracolonic disease manifestations. Indicates the recommended diagnostic algorhytm and early diagnosis in families. Three examples from daily practice should show some problems the treating doctor can meet. Displays treatment modalities and preventive measures; follow up, examinations and chemopreventive agents.