Ján Staško, Pavol Hollý, Miroslava Dobrotová, Peter Kubisz
Hemostasis represents one of the complex mechanisms that maintain the integrity of homeostasis. In physiological condition it provides fluidity of blood in the inactive vessel stream bed and leads to the cessation of bleeding from impaired vessel wall. It is controlled by the balancing harmony of procoagulant and anticoagulant mechanisms. Disorders of this equilibrium can be expressed as hemorrhagic or thrombophilic states. In this article there are the most frequent hemorrhagic states presented in survey as well as the contemporary possibilities of their targeting diagnostics, prevention and treatment.