Eva Szabóová, Miriam Kozárová, Dáša Kmecová, Ivan Tkáč
Risk tables often underestimate the real 10-year cardiovascular risk. Objectives: To determine the incidence of subclinical atherosclerosis on the sample of individuals without apparent cardiovascular affliction. Patients and methods: We examined 66 people (34 men, 32 women) at the age 35 - 50 years. We evaluated anamnesis, physical finding, laboratory parameters; we determined 10-year cardiovascular risk (Framingham, SCORE) as well as markers of subclinical atherosclerosis on the basis of the detection of functional or morphological changes in the arterial wall. Results: In 42.4 % of individuals with low calculated 10-year cardiovascular risk without apparent cardiovascular affliction we detected endothelial dysfunction or rigidity of the arterial wall. Conclusion: Frequent finding of subclinical atherosclerosis in people without apparent cardiovascular affliction calls attention to the need of individual risk stratification.