Pavol Murín, Peter Mitro
Cardiac dyssynchrony occurs when one portion of the wall contracts later than others. It is the consequence of electrical conduction delay, mostly caused by left bundle branch block. Dyssynchrony reduces both global pump function and heart efficiency. Cardiac resynchronization therapy results in substantial improvement in acute and long-term left ventricular performance of patients with chronic heart failure by retiming of contractions of dyssynchronous ventricular wall segments.