Miriam Kozárová, Mária Rašiová, Ľudmila Podracká
Conventional renal consequences of obesity include increased renal flow, glomerular hyperfiltration and renal hypertrophy. Proteinuria is another frequently observed complication of obesity with worldwide increasing prevalence. The exact aetiology of obesity-related glomerulopathy (ORG) remained unexplained for a long time. ORG characterized by proteinuria, normal serum albumin and absence of / or with only mild oedema may lead to terminal renal failure. Despite the fact that the first short-term studies of ORG have described its relatively benign clinical course, new data show a poor long-term prognosis for obese patients with histologically verified ORG. ORG should become a standard part of the differential diagnosis of chronic renal disease with proteinuria in obese patients.