Marián Mokáň, Peter Galajda, Martina Ondrušová, Mária Pšenková
Introduction and Objectives: The submitted national retrospective study evaluates the clinical efficacy of both available insulin analogues (glargine and detemir) and their impact on selected indicators of treatment success rate. Results: Levels of glycated haemoglobin HbA1c were non-significantly higher when setting patients to glargine at the beginning of the observation. For both analogues there was recorded a statistically significant decrease of HbA1c. Inputs and continuous data showed no significant difference. Decrease in fasting blood glucose levels was significant in both analogues; the difference in glycaemic improvement was not statistically significant. Only once there was registered the occurrence of severe daily hypoglycaemia in glargine regimen. Conclusion: The study confirmed the same clinical efficacy in both arms (glargine vs detemir), without statistically significant differences when comparing results from both branches of the treatment.