Increasing number of diabetic patients with renal complications worldwide is a burden for healthcare systems. Diabetic
patients with chronic kidney disease are the largest group from among patients on renal replacement therapy. A consistent
early screening of diabeticnephropathy usin gassessment of albuminuria and estimated glomerular filtration rate
is needed. The goal of treatment is to slow a progression of renal disease by achieving a good glycemic control and
recommended blood pressure values using angiotensin converting enzyme inhibitors or angiotensin receptor blockers.
Researchers are trying to elucidate cellular, molecular, hemodynamic and metabolic interactions in glomeruli in order
to institute more efficient target oriented therapy. European Renal Best Practice workgroup developed clinical practice
guideline on management of patients with diabetes and chronic kidney disease stage 3b or higher.