Lenka Bubernáková, Peter Hyrdel, Martin Schnierer, Peter Lipták, Rudolf Hyrdel
Small intestinal bacterial overgrowth is characterized by the presence of abnormal and excessive amounts of bacteria in
the small intestine. Quantitative diagnostic criterion is the presence of at least 105 colony – forming units of bacteria per
millilitre of jejunal aspirate. The most common clinical symptoms are bloating, flatulence, abdominalgia, nausea, dyspepsia,
fatigue, diarrhoea or constipation. Diagnosis of this common disease is complicated and difficult. There we have
breath test with glucose and lactulose, examination of jejunal aspirate is in our geographical conditions an exception.
Treatment of SIBO also has its limits, we often meet with insufficiently effective treatment and frequent recurrence.
The benefit in the coming years can be microbiological genetic methods, especially metagenomics and metabolomics.