Eduard Veseliny, Peter Jarčuška, Mária Zakuciová, Martin Janičko
The incidence of esophageal adenocarcinoma (EAC) has risen dramatically over the past three decades in western countries. The importance of Barrett’s esophagus (BE) derives from its potential to transform to adenocarcinoma. BE is characterized by endoscopically recognized displacement of the squamocolumnar junction proximal to the gastroesophageal junction, with replacement of squamous mucosa with columnar lined mucosa. Adenocarcinomas of the esophagus appear to arise from Barrett’s mucosa through progressive degrees of dysplasia, but the pathogenesis and natural history of this process are still unclear. In this article we show the current opinion and recommendations relating to diagnostics, surveillance and treatment of patients with Barrett’s esophagus.