Michaela Dzuriková, Marian Bátovský
Nowadays more than 25 diseases, syndromes, or other aberrations have been associated with the intestinal microbiota. Specific correlations have been made with potentially health-associated bacteria, such as some Bifidobacterium spp., Faecalibacterium prausnitzii and Akkermansia muciniphila. Antibiotic therapies are important in combating disease-causing microorganisms and maintaining host health. It is important to consider that antibiotics not only target pathogenic bacteria in the gut, but also can have damaging effects on the ecology of commensal species. This can reduce intrinsic colonization resistance and contribute to problems with antibiotic resistance, including lateral transfer of resistance genes. Solving of problems and questions regarding postantibiotic dysbiosis will be crucial for development of strategies, such as target therapeutics and probiotics, to prevent perturbations in the gut microbiota, the restoration of beneficial species and improvements in host health.