Management of patients with pancreatic tumours requires high-class diagnostics, which consists mainly of radiologic methods as ultrasound examination, computed tomography (CT) and magnetic resonance (MR). Decision on benign or malignant nature of the process is very demanding in many cases, as well as differential diagnostics between particular pathological processes, as e.g. chronic pancreatitis and pancreatic carcinoma, or between cystic tumours. Ultrasound examination is mainly the first modality which a patient encounters. CT and MRI examination follow and they better characterize pathological changes and in the case of tumorous changes they also allow for comments on the extent of infliction, operability of the process and metastatic infliction. In many cases the combination of particular methods is inevitable together with biopsy under USG or CT control. Decision on therapeutical process at serious findings requires multidisciplinary approach.