Petr Dítě, Ivo Novotný, Martin Liberda, Alice Bártková, Martina Bojková, Lenka Dovrtělová, Bohuslav Kianička
Introduction: The metabolic syndrome and its components belong to significant aetiologically risky factors of various
diseases afflicting various organs. The presence of at least three out of five values is required for metabolic syndrome
diagnosis. Metabolic syndrome is not just a condition inducing the disease of cardiovascular system, but it seems to be
also a risk factor of the gastrointestinal tract diseases.
1. Metabolic syndrome is a significant factor participating in the origination and course of acute pancreatitis, especially
related to its complicated course.
2. Long-term monitoring showed an importance of metabolic syndrome besides the course of chronic alcoholic pancreatitis,
but without impact on outer secretory capacity, but with relation to endocrine pancreatic function.
3. A very frequent finding in patients with metabolic syndrome and particularly with obesity is pancreatic steatosis. This
condition significantly influences namely function of pancreatic beta-cells.
Conclusion: Metabolic syndrome is an important factor in induction and course of So the therapy of obesity and generally
of metabolic syndrome has to be part of complex therapy in patients with pancreatic disease.