Martin Mrázik, Dušan Podmanický, Branislav Kunčak, Zuzana Zelinková
Authors present a case report of massive bleeding from jejunal angiodysplasia during the treatment with a new oral anticoagulant
(NOAC). The bleeding required surgical intervention with intraoperative endoscopic evaluation of the bleeding
origin and resection of a part of jejunum. Angiodysplasia is a common term designating a primary vascular degenerative
lesion of vascular ectasia or arteriovenous malformation. It is a common cause of GI bleeding and the lesions
are often multiple. The antiflogistic, antiagregant and anticoagulant medication including NOAC increases the risk of
bleeding from angiodysplasia. Diagnosis of small bowel bleeding is difficult. It is a cause of most cases of bleeding from
an unknown source – so-called obscure gastrointestinal bleeding (OGIB). The most common source of small bowel bleeding
are angiodysplasia, small bowel tumours, ulcers, Crohn disease and diverticula.