Jaroslava Richterová, Peter Ponťuch
Anaemia is a severe problem for patients suffering from chronic kidney disease (CKD). Anaemia is occasionaly observed among patients with glomerular filtration rate (GFR) of 30-60 ml/min (stage III of CKD). Majority of the patients with GFR < 30 ml/ min exhibit renal aneamia. Early treatment of anaemia with erythropoiesis stimulating agents (ESA) is recommended for patients in whom the haemoglobin concentration is < 110 g/l. Iron status should be measured and any deficiency corected before ESA is given. Patients with absolute iron deficiency should be treated with intravenous iron administration, at least at the start of ESA therapy. Whenever possible, blood transfusion should be avoided in order to minimaze the risk of HLA sensitization.
Keywords: anaemia, haemoglobin, iron, chronic kidney disease