Marta Chamulová, Peter Kružliak, Pavel Babušík
Insulin analogues are bringing many advantageous properties which ease insulin treatment in patients with diabetes type 1 and also type 2. They enable that the substitution treatment by insulin is getting closer to physiological secretion of insulin. In patients with diabetes type 2 it is then possible to decrease hyperinsulinaemia and in patients with overweight or obesity it is thanks to the decrease of saccharide input possible to achieve the body weight reduction. Variability of insulin acting in treatment by insulin analogues is decreasing and the treatment effect is thus more predictable. Due to it the treatment by insulin analogues is leading to decrease of number of hypoglycaemias and it is then safer for patients.