Arterial hypertension is one of the basic signs of chronic kidney disease. The incidence is growing up with progression of renal insufficiency. Its good management is extremely important for prevention of rise of cardiovascular complications. It is also important to take into consideration the metabolism of active substances with progressive decrease of glomerular filtration. Inhibitors of angiotensin converting enzyme (ACEi), angiotensin receptor blockers (ARB), diuretics and calcium channel blockers belong to the fundamental repertoire. Decline of intraglomerular tension by ACEi and ARB makes progression of renal diseases slower. In further decline of glomerular filtration renal possibility to keep natrium equilibrium between ingestion and excretion with its retention also decreases. Decrease of NaCl ingestion and reduction of overhydratation is the principal measure to achieve adequate hypertension correction at the beginning of dialysis treatment.