Beáta Girovská, Elena Tibenská
Coeliac disease, also known as coeliac sprue or gluten-sensitive enteropathy, is a widespread autoimmune disease, which is markedly underdiagnosed so far. One of the main reasons is mainly its polymorphic clinical picture with a frequent occurrence of extraintestinal symptoms. Within laboratory diagnostics there are few types of serological tests used, the most important are antibodies against tissue tranglutaminase, endomysium and deaminated gliadin peptides. These tests are also suitable for monitoring of compliance with gluten-free diet in already diagnosed patients with coeliac disease.