Alcohol is the most common cause of liver diseases in Slovakia. Alcohol is on the 3rd place among risk factors in Europe (after tobacco and hypertension). A save limit of alcohol consumption does not exist according to EASL guidelines (2012). Daily consumption of 25g of alcohol increases the risk of cirrhosis. Questionnaires are an essential tool for alcohol abuse detection. Increased levels of GMT, MCV, IgA, ratio AST/ALT more than 2 and carbohydrate-deficient transferrin are markers of higher alcohol consumption. The basis of the treatment is achieving of abstinence with help of a psychiatrist. Other methods are only supportive. Maddrey index or Glasgow score are useful in decision of corticoid or pentoxifylin treatment in alcoholic hepatitis. The liver transplantation is the last chance and it is possible after 6-month abstinence interval. Prognosis is much better, when abuse is eliminated.