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Časopis Internal medicine – Článok Determination of the male equivalent of polycystic ovary syndrome, depending on genetic factors in young males diseases and some cancerswith androgenetic alopecia focused on the hormonal profile and insulin resistance with dyslipidemia as risk factors for cardiovascular

Internal medicine

Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné
Téma: 

Determination of the male equivalent of polycystic ovary syndrome, depending on genetic factors in young males diseases and some cancerswith androgenetic alopecia focused on the hormonal profile and insulin resistance with dyslipidemia as risk factors for cardiovascular

Vincent Nagy, Ivica Lazúrová, Ingrid Dravecká, Jagienka Jautová, Janette Baloghová, Ladislav Valanský, Ľubomír Lachváč

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathy in women of reproductive age. Given the complexity of related symptoms of women with PCOS and signs of autosomal inheritance it is presumed to have been the male equivalent of PCOS. Objective of the study: The aim was to determine the existence of a male equivalent of polycystic ovary syndrome (PCOS) in younger men with hormonal imbalance and androgenic alopecia. Clinical Material and methods: In 2010-2011 we examined 22 patients with a mean age of 31.7 ± 7.9 years. For all we have done dermatological examination to exclude other causes of alopecia (16/22 in the skin biopsy), urology (sexology) and internal examination. There were examined plasma glucose and insulin levels, with the calculation of insulin resistance index HOMA (Homeostasis Model Assessment: glucose x insulin / 22.5), lipids: total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, hormone profile: total and free testosterone, free androgen index (FAI), sex hormone binding globulin (SHBG), follicle stimulating hormone (FSH), luteinizing hormone (LH) and anthropometric parameters: weight, height, waist circumference and body mass index (BMI: weight/height 2). Results: One patient (4.5 %) was confirmed by new onset type 2 diabetes and 3 patients (13.6 %) were confirmed by insulin resistance. Metabolic dyslipidaemia (hypertriglyceridaemia, low HDL cholesterol or elevated LDL cholesterol) occurred in 8 patients (36 %). Increased levels of testosterone were found in only 1 patient (4.5 %), increased FAI in 4 patients (18.18 %), and decreased SHBG in 2 subjects (9 %). Overweight and obesity have been confirmed in 40 % (9 patients). Conclusion: The existence of male equivalent of PCOS has not been proven yet, but there were confirmed the features of the metabolic syndrome, marginally higher fasting blood glucose, elevated LDL cholesterol and overweight. We found significant changes in hormonal parameters. For financial reasons, we examined only a limited number of patients without a control group, the study is continued.

Androgens, alopecia, PCOS, male equivalent, diabetes mellitus
Interná med. 2013; 13 (12): 535-538

Ročník 2013  Témy časopisu Internal medicine 12 / 2013

Overview works

Ľubomír Tomáš
Daniela Cupaníková
Vilma Voglová
Ivana Dedinská, Juraj Miklušica, Blažej Palkoci, Mazyar Fani, Ľudovít Laca

Vincent Nagy, Ivica Lazúrová, Ingrid Dravecká, Jagienka Jautová, Janette Baloghová, Ladislav Valanský, Ľubomír Lachváč
Nie sú dostupné žiadne voľne dostupné články
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REPRESENTATIVE OF CHAIRMAN
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MUDr. Viera Fedelešová, CSc.
prof. MUDr Martin Haluzík, CSc.
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2. Stenestrand U, Wallentin L. Swedish Register of Cardiac Intensive Care (RIKS-HIA): Early statin treatment following acute myocardial infarction and 1-year survival. JAMA 2001; 285(4): 430-436.
3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Send contributions in the e-mail to the address: stachova@amedi.sk
Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné