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Časopis Internal medicine – Článok Markers of aneurysm sac regression after endovascular aortic abdominal aneurysm repair

Internal medicine

Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné
Téma: Original works

Markers of aneurysm sac regression after endovascular aortic abdominal aneurysm repair

Mária Rašiová, Martin Koščo, Viera Habalová, Jozef Židzik, Eva Slabá, Matej Moščovič, Ľudmila Farkašová, Ivan Tkáč

Background: Optimal treatment result after endovascular aortic aneurysm repair (EVAR) is followed by significant
aneurysm sac regression without endoleak. The aim of our study was to evaluate diameter of abdominal aneurym
sac 24 months post-EVAR; to identify factors associated with sac regression and to determine the impact of sac regression
on all-cause mortality during long-term follow-up.
Methods: We retrospectively analyzed data of patients with infrarenal abdominal aortic aneurysm (AAA) treated
between January, 2010 and July, 2016. Sac diameter pre- and 24 months post-EVAR was determined by CT-angiography
at the site of maximum axial diameter. Sac regression was defined as at least 5 mm decrease in the sac
diameter in relation to the preprocedural diameter.
Results: Over the study period, 124 patients (116 men and 8 women) with mean age 71.2 ± 7.2 years were evaluated.
Sac regression was found in 45.2% of patients. Pacient with sac regression were older (73.0 vs 69.7 years in
patients with stable sac or sac expansion; p = 0.008) with significantly higher preprocedural fibrinogen levels (3.84
vs 3.47 g/l in patients with stable sac or sac expansion; p = 0.028). Persistent type II endoleak was inversely associated
with sac regression in univariate analysis and multivariate analysis after adjustment for hypertension, sex,
smoking and dyslipidaemia (OR 0.28; 95 % CI 0.11 – 0.70; p = 0.006). In other tested factors no correlation with
sac regression was found. During long-term follow-up, no difference was found in all-cause mortality between patients
with and without sac regression.
Conclusion: Higher preprocedural fibrinogen levels, older age and absence of persistent type II endoleak were
aneurysm sac regression predictive factors. No difference was found in long-term survival between groups of patients
with sac regression and without.

endovascular abdominal aortic aneurysm repair, abdominal aortic aneurysm, endoleak, fibrinogen, sac regression
Interná med. 2018; 18 (12): 493-498

Ročník 2018  Témy časopisu Internal medicine 12 / 2018

Original works

Mária Rašiová, Martin Koščo, Viera Habalová, Jozef Židzik, Eva Slabá, Matej Moščovič, Ľudmila Farkašová, Ivan Tkáč

Overview works

Viera Fábryová, Klára Sviteková, Branislav Fábry
Sylvia Dražilová
Štefan Raffáč, Juliana Gabzdilová
Štefan Sotak, Dominik Šafčák, Branislav Kučinský, Igor Andrašina
Andrej Dukát, Juraj Payer
Nie sú dostupné žiadne voľne dostupné články
CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Ivica Lazúrová, CSc. FRCP

REPRESENTATIVE OF CHAIRMAN
prof. MUDr. Juraj Payer, CSc., FRCP

MEMBERS OF THE EDITORIAL BOARD
doc. MUDr. Viera Fábryová, CSc.
MUDr. Viera Fedelešová, CSc.
prof. MUDr Martin Haluzík, CSc.
prof. MUDr. Štefan Hrušovský, CSc. Dr.SVS.
prof. MUDr. Rudolf Hyrdel, CSc.
doc. MUDr. Oľga Jurkovičová, CSc.
doc. MUDr. Zdenko Killinger, PhD.
doc. MUDr. Soňa Kiňová, PhD.
prof. MUDr. Peter Mitro, PhD.
doc. MUDr. Viliam Mojto, CSc., MHA
prof. MUDr. Karel Pacák, DrSc.
prof. MUDr. Juraj Payer, CSc., FRCP
doc. MUDr. Ján Podoba, CSc.
prof. MUDr. Igor Riečanský, DrSc.
doc. MUDr. Ján Staško, PhD.
doc. MUDr. Mária Szántová, PhD.
prof. MUDr. Ivan Tkáč, PhD.

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3. LIPID Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med 1998; 339: 1349-1357.
4. Jurkovičová O, Spitzerová H, Cagáň S. Komorové arytmie a náhla srdcová smrť pri akútnom infarkte myokardu. Bratisl Lek Listy 1997; 98: 379-389.
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Period 11x per year (july - august double issue)
1335-8359
The journal is indexed in the Slovak National Bibliography, Bibliographiia Medica Slovaca (BMS) and listed to citation database CiBaMed. All articles are reviewed. The publisher does not bear any responsibility for data and opinions of particular authors of the articles or advertisements. The articles on grey pages are company promotions or non reviewed information, an author is responsible for the content. Any reproduction of the content is allowed only with direct consent of the editorial office.
Predplatné
Internal medicine
Internal medicine
Peer - Reviewed Postgraduate Medical Journal.
Period 11x per year (july - august double issue)
Predplatné