Viera Vaterková, Jozef Záň, Marek Gembala
At present, cystic pancreatic lesions become a kind of up-to-date epidemy due to use of sensitive imaging technologies in routine practice. Even though there is little known about the prevalence of these lesions; we encounter these issues more frequently. They represent a heterogeneous group of entities with different biologic behaviour. Therefore, it is essential for a patient and his/her management to estimate the malignant potential of lesions correctly. Despite the rapid development of medical imaging modalities, diagnosis of cystic tumours of the pancreas stays imperfect. Combination of endosonographic lesion morphology and EUS-FNA with the cytological and biochemical cystic aspirate analysis is today still most accepted and quite frequently used and available technique. Unfortunately, regularly with suboptimal results. Existing biomarkers used to differentiate cystic lesions of the pancreas are insufficient. That is why hope is laid on new methods increasing the yield of EUS-FNA.