Ľudovít Laca, Mazyar Fani, Jozef Urdzik, Ján Janík, Marek Adámik, Juraj Miklušica, Rudolf Hyrdel
Carcinoids present rare tumors originating from chromaffine neuroendocrine Kultchitsky cells of the gastrointestinal tract which are components of diffuse neuroendocrine system (APUD). The cells produce various hormonally active substances that form often bizarre clinical pictures. Authors present case reports of three patients treated at the 2nd surgical klinic of Teaching hospital in Martin (MFN JLF UK) from January 1st 2004. Two patients had symptomatic form of malignant carcinoid and one patient was asymptomatic. The disease of one patient was controlled by eliminating hepatometastases by the use of radiofrequent ablation (RFA), the other one has been objectively for 30 months without any signs of relapse of the basic illness after radical surgical therapy and RFA of residual metastatic focus and elimination of symptoms of the illness. Progression of the illness of the third patient with palliative resection failed to be stopped so as relieving of clinical symptomatology and the patient died 9 months after surgical intervention. We can say that care of patients with malignant carcinoid with hepatometastases belongs to specialized gastroenterological workplace with experience in management of patients with neuroendocrine tumors and cooperating with surgical department experienced in liver surgery.