Laura Gombošová, Peter Jarčuška, Peter Bohuš, Vladimír Sihotský, Mária Zakuciová, Ivica Lazúrová
Hepatic sarcoidosis represents an extrapulmonary manifestation of systemic granulomatous disease. Hepatic involvement is documented in 20 - 90 % patients, rarely granulomatous hepatitis is the sole manifestation of disease. Published rates underestimate the frequency of disorder, because many of cases are undiagnosed or misdiagnosed. Extent of organ involvement with progressive fibrosis determines the prognosis of disease. Authors present a case of hepatic sarcoidosis mimicking a liver cirrhosis with ascites. Hepatic sarcoidosis as the first extrapulmonary manifestation of the systemic sarcoidosis was diagnosed by complete examinations, including histology. Spleen, retroperitoneal lymph nodes and the peritoneum were also affected. The disease was manifested by unclear long-standing cholestatic hepatopathy with progressive fatigue and loss of weight.